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Isolation and characterization of the recombinant human α-fetoprotein fragment corresponding to theC-terminal structural domain

✍ Scribed by O. A. Sharapova; N. V. Pozdnyakova; D. K. Laurinavichyute; M. S. Yurkova; G. A. Posypanova; S. M. Andronova; A. N. Fedorov; S. E. Severin; E. S. Severin


Book ID
111457120
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
798 KB
Volume
36
Category
Article
ISSN
1068-1620

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✍ Luisa Ronga; Pasquale Palladino; Gabriella Saviano; Teodorico Tancredi; Ettore B 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB

## Abstract The 173–195 segment corresponding to the helix 2 of the globular PrP domain is a good candidate to be one of the several ‘spots’ of intrinsic structural flexibility, which might induce local destabilization and concur to protein transformation, leading to aggregation‐prone conformations