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Preparation and characterization of a C-terminal fragment of pregnancy zone protein corresponding to the receptor-binding peptide from human α2-macroglobulin

✍ Scribed by Poul Erik H. Jensen; Luis F. Arbelaez; Vithaldas P. Shanbhag; Torgny Stigbrand


Book ID
113269759
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
400 KB
Volume
1293
Category
Article
ISSN
0167-4838

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## Abstract The 173–195 segment corresponding to the helix 2 of the globular PrP domain is a good candidate to be one of the several ‘spots’ of intrinsic structural flexibility, which might induce local destabilization and concur to protein transformation, leading to aggregation‐prone conformations