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Isolation and characterization of ten mutator alleles of the mitochondrial DNA polymerase-encoding MIP1 gene from Saccharomyces cerevisiae

✍ Scribed by Jingping Hu; Sylvie Vanderstraeten; Françoise Foury

Book ID
116132794
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
582 KB
Volume
160
Category
Article
ISSN
0378-1119

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Overexpression of the RNR1 gene rescues
Overexpression of the RNR1 gene rescues Saccharomyces cerevisiae mutants in the mitochondrial DNA polymerase-encoding MIP1 gene
✍ Lecrenier, Nicolas ;Foury, Françoise 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 930 KB

A multicopy suppressor gene which rescues the temperature-sensitive growth defect of Saccharomyces cerevisiae mutants in the mitochondrial DNA (mtDNA) polymerase-encoding MIP1 gene has been isolated and identified as the RNR1 gene. This gene, whose transcript is cell cycle-regulated and mainly expre