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Isolation and characterization of mutants of Escherichia coli K-12 which leak β-galactosidase

✍ Scribed by Kenneth Olden; T. Hastings Wilson

Book ID
115721768
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
680 KB
Volume
288
Category
Article
ISSN
0005-2736

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Degradation of missense mutant β-galacto
Degradation of missense mutant β-galactosidase proteins in Escherichia coli K-12
✍ Bergquist, P. L. ;Truman, Penelope 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 304 KB

Ten out of 43 missense mutations in the lacZ gene of Escherchia coli gave rise to polypeptide chains that were degraded in vivo. While many of the mutants appeared to be fully or partially CRM-, there appeared to be no obvious correlation between degradation, map position, altered subunit associatio