Amphotericin B resistance is recessive i
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Katsuhiko Hidaka; Shin-Ichi Akiyama; Michihiko Kuwano
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Article
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1981
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John Wiley and Sons
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English
β 486 KB
## Abstract Previous studies from our laboratory have shown that Chinese hamster V79 cells mutated to high level resistance to amphotericin B have a lower cellular level of cholesterol, the target molecule for the polyene antibiotic. Two amphotericin Bβresistant (AMB^R^) mutants were each hybridize