Isolated vitamin E deficiency
β Scribed by Carlayne E. Jackson; Anthony A. Amato; Richard J. Barohn
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 465 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
β¦ Synopsis
A 22-year-old man presented with progressive gait instability, tremor, and dysarthria since childhood. Electrophysiologic studies revealed a sensorimotor polyneuropathy. Laboratoty studies documented vitamin E deficiency; however, no gastrointestinal, hepatic, or lipoprotein disorder could be identified. Vitamin E therapy normalized the serum level, but there was no neurologic improvement. Isolated vitamin E deficiency, in the absence of lipid malabsorption, should be considered in the evaluation of children and adults with ataxia and peripheral neuropathy.
π SIMILAR VOLUMES
## Abstract Vitamin E levels were measured in the plasma of infants and children with various neuromuscular disorders. Seven of 8 infants with WerdnigβHoffmann disease (WHD) had a singificantly lower plasma vitmin E level (__p__ < 0.01) than ageβmatched normal controls, children with congenital myo
deficiency embryopathy due to a disorder of embryonic vitamin K metabolism.