Isolated limb perfusion with melphalan in the treatment of malignant melanoma
โ Scribed by Andrew S. Bulman; Crawford W. Jamieson
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 281 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0007-1323
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๐ SIMILAR VOLUMES
Subungual melanoma is rare and experience in treating this condition with isolated limb perfusion is limited. Between 1985 and 1990, 24 patients were treated by digital amputation and isolated limb perfusion with melphalan and mild hyperthermia. The disease was staged according to the M.D. Anderson
## Background: This retrospective study evaluated the benefit of using tumor necrosis factor (tnf) and melphalan administered via an isolated limb perfusion (ilp) in a series of patients with metastatic melanoma who failed initial ilp with chemotherapeutics. ## Methods: Seventeen patients with ex