Hyperthermic isolated perfusion with melphalan in the treatment of advanced malignant melanoma of the lower limb
β Scribed by A. I. Skene; A. S. Bulman; T. R. Williams; Mr J. Meirion Thomas; G. Westbury
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 301 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0007-1323
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π SIMILAR VOLUMES
Subungual melanoma is rare and experience in treating this condition with isolated limb perfusion is limited. Between 1985 and 1990, 24 patients were treated by digital amputation and isolated limb perfusion with melphalan and mild hyperthermia. The disease was staged according to the M.D. Anderson
Hyperthermic isolated limb perfusion (HILP) with various chemotherapeutic agents has been used for the local treatment of high-grade soft tissue sarcomas (STS) of the extremities, but in most cases, with a disappointing result. Most such regimens certainly should not be considered superior to surger