𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Isoindol-1-one Analogues of 4-(2‘-methoxyphenyl)-1-[2‘-[ N -(2‘‘-pyridyl)- p -iodobenzamido]ethyl]piperazine ( p -MPPI) as 5-HT 1A Receptor Ligands

✍ Scribed by Zhuang, Zhi-Ping; Kung, Mei-Ping; Mu, ; Kung, Hank F.


Book ID
126286186
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
184 KB
Volume
41
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


In vivo binding of [123I]4-(2′-methoxy p
✍ Mei-Ping Kung; Zhi-Ping Zhuang; Dana Frederick; Hank F. Kung 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 862 KB

The in vivo regional distribution and pharmacological profile of a novel iodinated phenylpiperazine derivative, [12311p-MPPI (4-(2'-methoxy-)phenyl-l-[2'-(N-2"pyridinyl)-p-iodobenzamido-Iethyl-piperazine), in the rat brain were evaluated for use as a potential in vivo imaging agent for 5-HTlA recept

2-[4-(o-methoxyphenyl)piperazin-1-ylmeth
✍ María L. López-Rodríguez; MaJosé Morcillo; MaLuisa Rosado; Bellinda Benhamu; Ant 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 246 KB

A series of 2-[~-(4-arylpiperazin-1-yl)aikyl]-1,3-dioxoperhydroimidazo[ 1,5-a]pyridine derivatives was prepared and evaluated for affinity at 5-HT~A and ct I receptors. The most promising analogue Ira bound at 5-HT~A sites with nanomolar affinity (/~.=31.7) and high selectivity over ~, D2 and 5-HT2A