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Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation

✍ Scribed by Rainer Haseneder; Stephan Kratzer; Ludwig von Meyer; Matthias Eder; Eberhard Kochs; Gerhard Rammes


Book ID
113588444
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
469 KB
Volume
623
Category
Article
ISSN
0014-2999

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Hippocampal long-term potentiation (LTP) is strongly associated with the acquisition of spatial memory and is attenuated by ethanol. Recent studies have shown that the inhibitory potency of ethanol against n-methyl-d-aspartate (NMDA) receptor-mediated synaptic activity is enhanced in hippocampal sli