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Hippocampal synaptic plasticity in streptozotocin-diabetic rats: impairment of long-term potentiation and facilitation of long-term depression

✍ Scribed by A. Kamal; G.-J. Biessels; I.J.A. Urban; W.H. Gispen


Book ID
117492729
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
173 KB
Volume
90
Category
Article
ISSN
0306-4522

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## Abstract Diacylglycerol (DAG) is an important signaling molecule at neuronal synapses. Generation of synaptic DAG is triggered by the activation of diverse surface receptors including __N__‐methyl‐D‐aspartate (NMDA) receptors and metabotropic glutamate receptors. The action of DAG is terminated