Isoelectric focusing of vitamin D binding protein (Gc): Genetic diversity in the populations of Iran
โ Scribed by S. S. Papiha; I. White; M. T. Akbari; D. D. Farhud
- Publisher
- Nature Publishing Group
- Year
- 1985
- Tongue
- English
- Weight
- 293 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1435-232X
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For the study of group specific component (Gc) and phosphoglucomutase (PGM1) polymorphism, isoelectric focusing was performed on eleven tribal and non-tribal populations of Himachal Pradesh, India. They were chosen to illustrate interregional and intraregional variations. The subtype frequencies of
Common and rare Gc phenotypes were analyzed by agarose gel electrophoresis immunofixation and by isoelectric focusing immunofixation before and after neuraminidase treatment. There is a difference between Gc types with double-band and with single-band patterns. Neuraminidase affects only Gc types wi