Isochromosome 17q in two cases of acute blast transformation in myeloproliferative disorders

✍ Scribed by A. McDermott; D. Romain; I. D. Fraser; G. L. Scott

• Book ID: 104705717
• Publisher: Springer
• Year: 1978
• Tongue: English
• Weight: 571 KB
• Volume: 45
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00286966

✦ Synopsis

Two cases of acute blast cell transformation in myeloproliferative disorders associated with a dicentric 17q isochromosome are reported. In both cases, the karyotypes also included a Philadelphia 9q;22q translocation, and in one case, an additional chromosome 8 (trisomy 8).