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Isochromosome 17q in cell lines of two cases of B cell chronic lymphocytic leukemia

✍ Scribed by M. Vahdati; H. Graafland; J.M. Emberger


Book ID
119102666
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
267 KB
Volume
9
Category
Article
ISSN
0165-4608

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## Abstract Deletion of chromosome region 11q22–q23 defines a subgroup of patients with B‐cell chronic lymphocytic leukemia (B‐CLL) characterized by poor survival. Although the tumor‐suppressor gene __ATM__ in the consensus deletion region was found to be biallelically inactivated in about one thir