Islet amyloid polypeptide is the major protein component of the islet amyloid of patients with Type 2 (noninsulin-dependent) diabetes mellitus. Since the synthesis of a structurally abnormal or mutant protein may contribute to the formation of amyloid deposits, we have examined the possibility that
Islet amyloid in type 2 (non-insulin-dependent) diabetes
β Scribed by A. CLARK; S. B. P. CHARGE; M. K. BADMAN; E. J. P. DE KONING
- Book ID
- 114823214
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 550 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0365-5555
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π SIMILAR VOLUMES
Fasting plasma islet amyloid polypeptide concentrations and their responses to an oral glucose load were determined in non-diabetic control subjects and patients with abnormal glucose tolerance in relation to the responses of insulin or C-peptide. Plasma islet amyloid polypeptide was measured by rad
Type 2 (non-insulin-dependent) diabetes is associated with the deposition of islet amyloid. The major formative peptide, islet amyloid polypeptide, has recently been characterised and an abnormality of the structure or expression of this gene is a possible candidate for the inherited component of Ty