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Is ursodeoxycholic acid an effective treatment for primary sclerosing cholangitis?

✍ Scribed by Chazouillères, O.; Poupon, R.; Capron, J.P.; Metman, E.H.; Dhumeaux, D.; Amouretti, M.; Couzigou, P.; Labavle, D.; Trinchet, J.C.

Book ID: 123445065
Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 70 KB
Volume: 9
Category: Article
ISSN: 0168-8278
DOI: 10.1016/0168-8278(89)90452-2

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Previous controlled trials are inconclusive regarding the efficacy of ursodeoxycholic acid (UDCA) for treating primary sclerosing cholangitis (PSC). One hundred fifty adult patients with PSC were enrolled in a long-term, randomized, double-blind controlled trial of highdose UDCA (28-30 mg/kg/day) ve