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Is there a role for IL-18 in Host Defense against HBV Infection?

✍ Scribed by Karra, Vijay Kumar; Gumma, Phani Kumar; Ruttala, Rajesh; Chowdhary, Soumyajyothi; Pollipalli, Sunil Kumar; Chakrvarthi, Anitha; Kar, Premashis


Book ID
122182136
Publisher
Elsevier
Year
2014
Tongue
English
Weight
92 KB
Volume
4
Category
Article
ISSN
0973-6883

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## Abstract Tuberculosis remains the most hazardous bacterial infection worldwide. The causative agent, __Mycobacterium tuberculosis__, is a facultative intracellular pathogen of resting MΞ¦. IFN‐γ secreted by natural killer, CD4 Th 1 and CD8 T cells upon instruction by IL‐12 and ‐18 activates MΞ¦ to