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Is the polymorphic microsatellite repeat of the dopamine β-hydroxylase gene associated with biochemical variability of the catecholamine pathway in schizophrenia?

✍ Scribed by Jun Wei; Hai-Min Xu; C.N. Ramchand; Gwynneth P. Hemmings


Book ID
118510856
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
485 KB
Volume
41
Category
Article
ISSN
0006-3223

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The presence of a polymorphic (GT) n repeat, a microsatellite repeat, at the human dopamine ␤-hydroxylase (DBH) gene had been previously investigated in healthy people and in schizophrenic patients. The different DBH genotypes had been found to be associated to different DBH biochemical function, bu