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Is the dopaminergic system involved in the central effects of nicotine in mice?

✍ Scribed by M. I. Damaj; B. R. Martin

Publisher
Springer
Year
1993
Tongue
English
Weight
482 KB
Volume
111
Category
Article
ISSN
0033-3158

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Nicotine (0.16--0.50 mg/kg, SC) was found to exert a potent antinociceptive action on thermal stimuli as measured by the tail-flick test. This antinociceptive action of nicotine could be blocked by centrally active nicotinic or muscarinic blockers implicating both classes of cholinergic receptors in