Nicotine (0.16--0.50 mg/kg, SC) was found to exert a potent antinociceptive action on thermal stimuli as measured by the tail-flick test. This antinociceptive action of nicotine could be blocked by centrally active nicotinic or muscarinic blockers implicating both classes of cholinergic receptors in
Effects of subchronic nicotine administration on central dopaminergic mechanisms in the rat
β Scribed by Laurence A. Carr; Peter P. Rowell; William M. Pierce
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 451 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Acute and subchronic administration of NβmethylβDβaspartate antagonists to rats in the early postnatal period has been reported to produce widespread and selectively cortical neurotoxicity, respectively. To resolve this apparent discrepancy, we sought to clarify these data by determinin
Organophosphorus (OP) pesticides are considered to be environmental contaminants, and chronic exposure to low levels through the diet may affect drug action. To study this possible interaction, ethyl parathion was administered by intubation to female rats for 35 consecutive days at a dose of 0.05 or