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Is the detection of fucose cancer markers by 2D 1H NMR unequivocal?

✍ Scribed by P. S. Phillips; F. G. Herring


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
369 KB
Volume
15
Category
Article
ISSN
0740-3194

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✦ Synopsis


Abstract

Fucose is believed to be a marker for cancer that may be detectable by the 2D proton NMR (COSY) of human plasma. However, the COSY technique is time consuming and prone to error. These problems may be alleviated by using the SUPERCOSY pulse sequence; this technique shows that there are many other cross peaks in the region (1.3, 4.2 ppm) which are not readily distinguishable from fucose. Β© 1990 Academic Press, Inc.


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