Is severe recurrent hepatitis C more common after adult living donor liver transplantation?

✍ Scribed by Mark W. Russo; Roshan Shrestha

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 79 KB
• Volume: 40
• Category: Article
• ISSN: 0270-9139
• DOI: 10.1002/hep.20418

✦ Synopsis

No differences between LDLT and DD

Shiffman 1 23 USA, single center yes No patients developed cirrhosis on liver biopsy @ 3 years Russo 10 279 USA, UNOS database no 2-year graft survival 72% LDLT and 75% DD Bozorgzadeh 11 35 USA, single center no No difference in HCV recurrence on liver biopsy Gordon 5 (abstract) 19 USA, single center no Survival 92% in both groups at 36 months Pan 7 (abstract) 15 USA, single center no HCV recurrence on liver biopsy 47% LDLT vs. 65% DD Fahmy 8 (abstract) 33 USA, single center no Graft loss from recurrent hepatitis C 3% LDLT vs. 7.7% DD Vlierberghe 9 (abstract) 17 Belgium, Italy no HCV recurrence on liver biopsy 35% LDLT vs. 38% DD Trotter 4 (abstract) 41 USA, 2 centers no No difference in rate of graft loss from HCV in LDLT and DD group LDLT worse Garcia-Retortillo 12 22 Spain yes Cirrhosis or decompensated liver disease in 45% LDLT vs. 22% DD at 2 years, P ϭ .019 Gaglio 6 23 USA, single center no HCV recurrence on liver biopsy, graft failure were similar in LDLT and DD group, cholestatic hepatitis higher in LDLT group, 17% vs. 0%, P ϭ .001 Ghobrial 3 (abstract) 9 USA, single center no HCV recurrence on liver biopsy in 86% LDLT vs. 30% DD, P ϭ .004