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Is response to antiviral treatment influenced by hepatitis B virus genotype?

✍ Scribed by Sara Raimondi; Patrick Maisonneuve; Savino Bruno; Mario U. Mondelli


Book ID
116652074
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
508 KB
Volume
52
Category
Article
ISSN
0168-8278

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## Abstract No data on antiviral response of HBV genotypes E–H are available so far although these HBV genotypes contribute significantly to the global HBV burden. Of 49 patients with HBV genotypes E–H, 23 received interferon (IFN)‐alpha, 12 nucleos(t)ide analogues and 14 patients were untreated. H

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The viral genotype may influence the response to interferon sion and more efficient antiviral immune response, is still (IFN) treatment in chronic hepatitis C virus (HCV) infection. unclear. To characterize potential mechanisms responsible for this ef-Several factors including viral load, disease se