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Is Cognition Altered in the Eker Rat Model of Tuberous Sclerosis Complex?

โœ Scribed by Carl E. Stafstrom


Book ID
109138426
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
62 KB
Volume
6
Category
Article
ISSN
1535-7597

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## Abstract We have recently identified on rat chromosome 10q a germline mutation in the tuberous sclerosis gene(__Tsc2__), the gene predisposing to renal carcinoma(a) in the Eker rat. The homozygous mutant condition is lethal at around the 13th day of fetal life. In heterozygotes, RCs invariably d