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Is a Klebsiella plasmid involved in the aetiology of ankylosing spondylitis in HLA-b27-positive individuals?

✍ Scribed by Fiona H. Cameron; Pamela J. Russell; John Sullivan; Andrew F. Geczy

Book ID
119089253
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
633 KB
Volume
20
Category
Article
ISSN
0161-5890

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## Abstract The present study was performed on 61 HLA‐B27 positive first‐degree relatives and 40 HLA‐B27 negative relatives of 20 HLA‐B27 positive probands with ankylosing spondylitis (AS). Of 24 HLA‐B27 positive relatives 45 years or older, 21% had AS and 38% sacroiliitis. The HLA‐B27 negative rel

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A comparative study of HLA genes in HLA–B27 positive ankylosing spondylitis and HLA–B27 positive peripheral reactive arthritis
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## Objective: To determine whether hla-b27 positive patients with ankylosing spondylitis (as) and reactive arthritis (rea) share additional hla factors that confer disease susceptibility. ## Methods: Hla class i antigens were typed serologically, and class ii antigens molecularly, in samples take