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Irreversible in vivo binding of thiabendazole to macromolecules in pregnant mice and its relation to teratogenicity

โœ Scribed by Yoneyama, M.; Ogata, A.; Hiraga, K.


Book ID
122510115
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
298 KB
Volume
23
Category
Article
ISSN
0278-6915

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1. 14C-labelled trichloroethylene was injected i.p. into male mice (10 mumole/g of b.w.). The radioactivity irreversibly bound to hepatic protein reached highest levels after 6 h: 2 nmole/mg in cytosol protein, 4.4 nmole/mg in mitochondrial protein, and 7.6 nmole/mg in microsomal protein. 2. The com