In response to a diverse array of signals, IkappaBalpha is targeted for phosphorylation-dependent degradation by the proteasome, thereby activating NF-kappaB. Here we demonstrate a role of the cleavage product of IkappaBalpha in various death signals. During apoptosis of NIH3T3, Jurkat, Rat-1, and L
Irradiation leads to sensitization of hepatocytes to TNF-α-mediated apoptosis by upregulation of IκB expression
✍ Scribed by Hakan Gürleyen; Hans Christiansen; Khodr Tello; Joszef Dudas; Robert M. Hermann; Margret Rave-Fränk; Clemens F. Hess; Giuliano Ramadori; Bernhard Saile
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 588 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0301-634X
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