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Iron-Catalyzed Oxidation of Tertiary Amines: Synthesis of β-1,3-Dicarbonyl Aldehydes by Three-Component C–C Couplings

✍ Scribed by Liu, Weiping; Liu, Jinhua; Ogawa, Daisuke; Nishihara, Yasushi; Guo, Xingwei; Li, Zhiping


Book ID
120753204
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
926 KB
Volume
13
Category
Article
ISSN
1523-7060

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An efficient three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in nearly quantitative yields using nanocrystalline CuO as a catalyst is described. Structurally divergent aldehydes and amines were converted to the corresponding propargylamines. The reaction does no