Iron-Catalyzed Enantioselective Hydrosilylation of Ketones
✍ Scribed by Nadim S. Shaikh; Stephan Enthaler; Kathrin Junge; Matthias Beller
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 353 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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## Abstract Iron‐catalyzed hydrosilylation is one of the most popular reduction reactions owing to the high natural abundance, low cost and low toxicity of iron and silicon. This paper introduces an advance in iron‐catalyzed hydrosilylation of olefins, aldehydes, ketones and amides. Some reactions
## Abstract magnified image Chiral macrocyclic tetra‐ and hexamine macrocycles derived from __trans__‐1,2‐diaminocyclohexane (DACH) in complexes with diethylzinc efficiently catalyze the asymmetric hydrosilylation of aryl alkyl ketones with enantiomeric excess of the product up to 89%. The cyclic