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Iron-Catalyzed Aminohydroxylation of Olefins

✍ Scribed by Williamson, Kevin S.; Yoon, Tehshik P.


Book ID
120317584
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
177 KB
Volume
132
Category
Article
ISSN
0002-7863

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The osmium-catalyzed aminohydroxylation
✍ Wallace Pringle; K.Barry Sharpless πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 212 KB

The Baylis-Hillman class of olefins undergoes a facile osmium-catalyzed aminohydroxylation reaction. The diastereoselectivity for the aminohydroxylation is influenced by the aldehyde-derived substituent, while the acrylate-derived substituent has a minimal effect. A variety of derivatives and close