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Copper(II)-Catalyzed Aminohydroxylation of Olefins

โœ Scribed by Michaelis, David J.; Shaffer, Christopher J.; Yoon, Tehshik P.


Book ID
124096304
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
53 KB
Volume
129
Category
Article
ISSN
0002-7863

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The Baylis-Hillman class of olefins undergoes a facile osmium-catalyzed aminohydroxylation reaction. The diastereoselectivity for the aminohydroxylation is influenced by the aldehyde-derived substituent, while the acrylate-derived substituent has a minimal effect. A variety of derivatives and close