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Iron and inflammation: cross-talk between pathways regulating hepcidin

✍ Scribed by Robert E. Fleming

Book ID
105796708
Publisher
Springer
Year
2008
Tongue
English
Weight
118 KB
Volume
86
Category
Article
ISSN
0946-2716

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The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors.