Iridium-Catalyzed Asymmetric Hydrogenation of 3-Substituted 2H-1,4-Benzoxazines
✍ Scribed by Kai Gao; Chang-Bin Yu; Duo-Sheng Wang; Yong-Gui Zhou
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 220 KB
- Volume
- 354
- Category
- Article
- ISSN
- 1615-4150
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In some foregoing communications"'. we reported the synthesis and anorectic activity of some thiazolo-and thiazinoperimidine derivatives. As an extension of our study in this series, we wish now to describe the method of fusing a 1,2,4-triazole component onto the perimidine nucleus. Theoretically, t
## Abstract A highly efficient and general iridium‐difluorphos‐catalyzed asymmetric hydrogenation of diverse 2‐alkyl‐ and 2‐aryl‐substituted quinoxalines into biologically and pharmaceutically relevant 2‐substituted‐1,2,3,4‐tetrahydroquinoxaline units has been developed. High isolated yields and ex
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