𝔖 Bobbio Scriptorium
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Ionic liquid mediated synthesis of peptide nucleic acids dimers

✍ Scribed by Poletti, Laura; Giannini, Clelia


Book ID
118275995
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
245 KB
Volume
69
Category
Article
ISSN
0040-4020

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Suitably protected linear precursors of cyclic PNAs can be readily obtained by BOP/DiPEA coupling of the corresponding sub-monomers. Conversion of the linear PNA dimers into the pentafluorophenyl esters allows cyclization by intramolecular attack of the deprotected primary amino function under dilut