Ion pair extraction of pharmaceutical amines. Role of dipolar solvating agents in extraction of dextromethorphan
โ Scribed by Higuchi, Takeru; Michaelis, Arthur F.; Tan, T.; Hurwitz, Arthur R.
- Book ID
- 120077861
- Publisher
- American Chemical Society
- Year
- 1967
- Tongue
- English
- Weight
- 561 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0003-2700
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๐ SIMILAR VOLUMES
The use of ion-pair extraction data to obtain group contribution values necessitates an assumption of countcrion independency. This assumption was examined in the present study, using the extraction of four tricyclic antidepressants with several anions as examples. It was found t o be valid, and a c
Studies on the influence of temperature on the distribution ratio of pharmaceutical ammonium species paired with various anions and between aqueous and organic phases have permitted determination of thermodynamic parameters associated with these extractive processes. Unlike transfer of uncharged sol