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Ion-exchange chromatography of the streptomycin complex

โœ Scribed by Pereira, J. N.


Publisher
Wiley (John Wiley & Sons)
Year
1961
Weight
322 KB
Volume
3
Category
Article
ISSN
0368-1467

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โœฆ Synopsis


Abstract

Various studies have revealed the presence of several maltolproducing compounds in streptomycin preparations. These previous studies have utilized the techniques of counterโ€current distribution, column chromatography, paper chromatography, and electrophoresis. A system of cationโ€exchange chromatography has been reported which separates, at least partially, six components of the streptomycin complex. This technique involves the use of a gradient elution procedure.

In addition to five maltolโ€producing compounds, another member of the complex is reported. The possible significance of such a compound is discussed.


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