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Iodine–Methanol-promoted Oxidation of 2-Aryl-1,2,3,4-tetrahydro-4-quinolones to 2-Aryl-4-methoxyquinolines

✍ Scribed by Mphahlele, Malose J.; Mogamisi, Fidelia K.; Tsanwani, Mutshutshu; Hlatshwayo, Sebayitseng M.; Mampa, Richard M.


Book ID
119974310
Publisher
Science Reviews 2000 Ltd
Year
1999
Tongue
English
Weight
119 KB
Volume
12
Category
Article
ISSN
0308-2342

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Easily accessible 2-aryl-l,2,3,4-tetrahydro-4-quinolones are readily oxidized to the corresponding 4-alkoxy-2-arylquinolines using a relatively safe hypervalent iodine reagent, [hydroxy (tosyloxy)iodo]benzene (HTIB), in high yields, thus providing a concise route to an important class of naturally o