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Iodine(+1) reduction by hydrogen peroxide

โœ Scribed by G. Schmitz


Book ID
110184631
Publisher
International Academic Publishing Co (Nauka/Interperiodica)
Year
2009
Tongue
English
Weight
202 KB
Volume
83
Category
Article
ISSN
0036-0244

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Green iodination of pyrazoles with iodin
โœ Mary M. Kim; Rebecca T. Ruck; Dalian Zhao; Mark A. Huffman ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 105 KB

In this Letter, we describe a practical, green iodination of pyrazoles to form the corresponding 4-iodopyrazole derivatives. The reaction takes place in water, using only 0.5 equiv of iodine and 0.6 equiv of hydrogen peroxide, a system that generates water as the only reaction by-product.