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Green iodination of pyrazoles with iodine/hydrogen peroxide in water

✍ Scribed by Mary M. Kim; Rebecca T. Ruck; Dalian Zhao; Mark A. Huffman

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
105 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

In this Letter, we describe a practical, green iodination of pyrazoles to form the corresponding 4-iodopyrazole derivatives. The reaction takes place in water, using only 0.5 equiv of iodine and 0.6 equiv of hydrogen peroxide, a system that generates water as the only reaction by-product.

πŸ“œ SIMILAR VOLUMES

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✍ Jasminka Pavlinac; Kenneth K. Laali; Marko Zupan; Stojan Stavber πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons βš– 39 KB πŸ‘ 2 views

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