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Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation

✍ Scribed by Zhang, L; Sharma, S; Hershman, J M; Brent, G A; Dubinett, S M; Huang, M

Book ID: 110019277
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 344 KB
Volume: 13
Category: Article
ISSN: 0929-1903
DOI: 10.1038/sj.cgt.7700875

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## Abstract Akt/protein kinase B signaling is very important for cancer cell survival and growth when cells are exposed to various apoptotic stimuli. Akt is constitutively activated in NSCLC cells and is a potential target for enhancing the cytotoxicity of chemotherapeutic agents in treatment of NS