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Involvement of vacuolar H+-ATPase in incorporation of risedronate into osteoclasts

✍ Scribed by M Takami; K Suda; T Sahara; K Itoh; K Nagai; T Sasaki; N Udagawa; N Takahashi


Book ID
117807811
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
583 KB
Volume
32
Category
Article
ISSN
8756-3282

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## Abstract Although bisphosphonates have been shown to be potent inhibitors of osteoclast‐mediated bone resorption in vivo and in vitro and are used as therapeutic agents in hyper‐resorptive bone diseases such as Paget disease or hypercalcemia of malignancy, their exact biochemical target(s) and m