Intravenous injection of lipopolysaccharide and Dg a l a c t d e , at doses of 0.2 pg/kg and 800 mg/kg, respectively, elicited massive hepatic necrosis within 24 hr in C3HMeN mice. The plasma L-alanine aminotransferase (ALT, E.C. 2.6.1.2) or L-aspartate aminotransferase (AST, E.C. 2.6.1.1) activitie
Involvement of tumor necrosis factor-? in glomerular injury
โ Scribed by Baud, Laurent ;Fouqueray, Bruno ;Philippe, Carole
- Book ID
- 104659299
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 660 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0344-4325
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Although hepatic ischemia-reperfusion (IR) injury is partially mediated by tumor necrosis factor-alpha (TNF), we recently found that low-dose TNF before IR is hepatoprotective. We examined the seemingly conflicting roles of TNF in mediating liver injury in a partial hepatic IR model using TNF gene k
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