## Abstract Severe injury deranges immune function and increases the risk of sepsis and multiple organ failure. Kupffer cells play a major role in mediating posttraumatic immune responses, in part via different Tollโlike receptors (TLR). Although mitogenโactivated protein kinases (MAPK) are key ele
Involvement of the TLR4 (Toll-like receptor4) signaling pathway in palmitate-induced INS-1 beta cell death
โ Scribed by Sung-Mi Lee; Sung-E Choi; Ji-Hyun Lee; Jung-Jin Lee; Ik-Rak Jung; Soo-Jin Lee; Kwan-Woo Lee; Yup Kang
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 492 KB
- Volume
- 354
- Category
- Article
- ISSN
- 0300-8177
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## Abstract DRG cells have been found to undergo apoptosis and necrosis after oxidized lowโdensity lipoprotein (oxLDL) stimulation in vitro. However, the mechanism of oxLDLโinduced DRG cell death is unclear. For this reason, we studied the expression of two potential oxLDL receptors: lectinโlike ox