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Involvement of the glucocorticoid receptor in stress-induced apoptosis of leukemic cells

✍ Scribed by Smets, L A; Salomons, G; Van Rooij, H; van den Berg, J


Book ID
110053770
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
239 KB
Volume
12
Category
Article
ISSN
0887-6924

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The application of glucocorticoids (GC') in human leukemia is based on apoptosis induction but is often hampered by GC resistance. To delineate resistance mechanisms, we examined 5 GC-resistant leukemic cell lines, termed CEM-C7.RI-R5, isolated from the GC-sensitive human acute-1-cell-leukemic line,