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Gene networks in glucocorticoid-evoked apoptosis of leukemic cells

✍ Scribed by M.Scott Webb; Aaron L. Miller; Betty H. Johnson; Yuriy Fofanov; Tongbin Li; Thomas G. Wood; E.Brad Thompson

Book ID
117668545
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
104 KB
Volume
85
Category
Article
ISSN
0960-0760

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The application of glucocorticoids (GC') in human leukemia is based on apoptosis induction but is often hampered by GC resistance. To delineate resistance mechanisms, we examined 5 GC-resistant leukemic cell lines, termed CEM-C7.RI-R5, isolated from the GC-sensitive human acute-1-cell-leukemic line,