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Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimurium

✍ Scribed by Galán, Jorge E.; Pace, John; Hayman, Michael J.


Book ID
109780875
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
265 KB
Volume
357
Category
Article
ISSN
0028-0836

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Incubation of Swiss mouse 3T3 cells at 37°C with bovine brain-derived growth factor (BDGF) decreased the cell surface '251-EGF binding activity of these cells by 70-80%. This down-modulation of the EGF receptor by BDGF was time, temperature, and dose dependent. Scatchard plot analysis indicated that