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Involvement of the DNA mismatch repair system in antineoplastic drug resistance

โœ Scribed by Hermann Lage; Manfred Dietel

Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
187 KB
Volume
125
Category
Article
ISSN
1432-1335

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## Abstract DNA mismatch repair (MMR) is one of the several enzyme systems involved in DNA homeostasis. DNA MMR is involved in the repair of specific types of errors that occur during new DNA synthesis; loss of this system leads to an accelerated accumulation of potential mutations, and predisposes