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Involvement of the antiplatelet activity of magnesium sulfate in suppression of protein kinase C and the Na+/H+exchanger

✍ Scribed by George Hsiao; Ming-Yi Shen; Duen-Suey Chou; Chien-Huang Lin; Tzeng-Fu Chen; Joen-Rong Sheu


Publisher
BioMed Central
Year
2004
Tongue
English
Weight
977 KB
Volume
11
Category
Article
ISSN
1021-7770

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The insulin modulation of Na-H antiport in rat hepatocytes was studied using the fluorescent, pH-sensitive intracellular probe, 2',7' bis (carboxyethyl)-5(6)-car- boxyfluorescein (BCECF). Our data show that insulin stimulates the Na-H antiport. The dose-response of insulin effect shows a behavior ty