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Involvement of the .alpha. chain in fibrin clot formation. Effect of monoclonal antibodies

✍ Scribed by Cierniewski, Czeslaw S.; Budzynski, Andrei Z.


Book ID
127130636
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
771 KB
Volume
31
Category
Article
ISSN
0006-2960

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The influence of Zn+' on fibrin clot formation was investigated by measuring its effect on the clotting times of fibrinogen exposed to thrombin. It was observed with either human or bovine thrombin that 0.01-0.1 mM Zn+2 induced significant reductions of clotting times in a concentration-dependent ma