The influence of Zn+' on fibrin clot formation was investigated by measuring its effect on the clotting times of fibrinogen exposed to thrombin. It was observed with either human or bovine thrombin that 0.01-0.1 mM Zn+2 induced significant reductions of clotting times in a concentration-dependent ma
Effect of Oxidation-Modified Fibrinogen on the Formation and Lysis of Fibrin Clot in the Plasma
โ Scribed by A. P. Piryazev; A. V. Aseichev; O. A. Azizova
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 303 KB
- Volume
- 148
- Category
- Article
- ISSN
- 0007-4888
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The elastic modulus (G') of factor XIIIa induced fibrinogen gels was found to be substantially lower than the G' of fibrin gels that were formed by clotting fibrinogen with thrombin. The addition of fibronectin and/or the reducing reagent dithiothreitol (DTT) to the factor XIIIa coagulation mixture
## Abstract The morphology of fibrin strongly depends on solvent medium, as shown by clotting experiments carried out in the presence of different salts. The clots were characterized by electron microscopy and spectrophotometric methods; the kinetics of gelation were determined. In the presence of